Research Chemical Designation & Liability

Compounds indexed in the MinMaxMuscle archive are strictly for laboratory research and development. They are NOT approved for human consumption. Theoretical dosing data is aggregated from clinical literature and must not be construed as medical instruction. Professional medical consultation is mandatory prior to any research application.

Full Disclaimer
Archive Identifier

Argireline

Skin Care

Molecular Dossier

  • Rank Index: 62
  • Status: Cosmetic Grade
  • What does this mean?
  • Molecular Structure: MW: 888.98 g/mol | Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 | 6 AAs

About Argireline

Hexapeptide-3 (Acetyl Hexapeptide-3) that competitively inhibits SNARE complex formation, reducing muscle contraction signals in the skin. Widely studied in clinical cosmetology showing measurable reduction in periorbital wrinkle depth. Works synergistically with GHK-Cu and Leuphasyl in anti-aging formulations.

Clinical Focus

Topical Wrinkle Reduction, Facial Muscle Relaxation, Collagen Support

Archival Aliases

Acetyl Hexapeptide-3, Acetyl Hexapeptide-8, Argireline Amplified

Frequently Asked Questions

Clinical Data Matrix

Parameter Clinical Value
Molecular Weight MW: 888.98 g/mol | Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 | 6 AAs
Primary Pathway Skin Care
Research Phase Cosmetic Grade

Clinical Pros

  • Highly selective receptor modulation
  • Documented efficacy in Phase II trials
  • Minimal systemic cross-reactivity

Research Limitations

  • Limited long-term human data
  • Strict storage and reconstitution requirements
  • Potential for acute homeostatic feedback loops

Community Discussion

Share your questions and experiences with other researchers in the forum.

Discuss in Forum

Clinical Reference Nodes

[REF 1] pubmed.ncbi.nlm.nih.gov
[REF 2] ncbi.nlm.nih.gov

Data Verified: 2026-04-14

Synergistic Matrix